Platelet Rich fibrin
Platelet rich fibrin (PRF) is exactly what the name suggests. The substance is a by-product of blood that is rich in platelets. New technology permits our doctors to harvest and produce a sufficient quantity of platelets from only 10cc (2 teaspoons) of blood drawn from the patient while they are having outpatient surgery. Platelets contain growth factors which promote cell growth, proliferation, healing, and cellular differentiation. To you, this means decreased healing time and less discomfort with surgical procedures.
Why All The Excitement About PRF?
PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These GF (platelet derived growth factors PGDF, transforming growth factor beta TGF, and insulin-like growth factor ILGF) function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors are released into the surgical site, the more stem cells are stimulated to produce new host tissue. Thus, one can easily see that PRF permits the body to heal faster and more efficiently.
PRF Has Many Clinical Applications
- Covering/securing bone grafts for dental implants
- Speeding repair of bone defects after removal of teeth or small cysts, especially in medially-compromised patients (smokers, diabetics, on blood thinners, on bisphosphonates, etc)
- Repairing communications between the sinus and oral cavity
- Preventing dry sockets
PRF Also Has Many Advantages
SAFETY: PRF is a by-product of the patient’s own blood, therefore, there is no risk of disease transmission.
CONVENIENCE: PRF can be generated in the doctors office while the patient is undergoing an outpatient surgical procedure, such as placement of dental implants or extraction of teeth.
FASTER HEALING: The supersaturation of the wound with PRF, and thus growth factors, produces an increase of tissue synthesis and thus faster tissue regeneration.
COST EFFECTIVENESS: Since PRF harvesting is done with only 10cc of blood in the doctors office, the patient need not incur the expense of a harvesting procedure in the hospital or at the blood bank.
EASE OF USE: PRF is easy to handle and actually improves the ease of application of bone substitute materials and bone grafting products by making them more gel-like.
Frequently Asked Questions About PRF
IS PRF SAFE? Yes. During the outpatient surgical procedure a small amount of your own blood is drawn via the IV. This blood is then placed in the PRF centrifuge machine and spun. In less than 15 minutes, the PRF is formed and ready to use.
SHOULD PRF BE USED IN ALL BONE-GRAFTING CASES? Not always. In some cases, there is no need for PRF. However, in the majority of cases, application of PRF to the graft will increase the final amount of bone present in addition to making the wound heal faster and more efficiently.
WILL MY INSURANCE COVER THE COSTS? Unfortunately not. The cost of the PRF application (only $50 per 10cc tube) is paid by the patient.
CAN PRF BE USED ALONE TO STIMULATE BONE FORMATION? No. PRF must be mixed with either the patients own bone, a bone substitute material such as demineralized freeze-dried bone, or a synthetic bone product, such as BIO-OSS.
ARE THERE ANY CONTRAINDICATIONS TO PRF? None!